2b21: Difference between revisions

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[[Image:2b21.gif|left|200px]]<br /><applet load="2b21" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2b21, resolution 2.4&Aring;" />
'''RADA Recombinase in complex with AMPPNP at pH 6.0'''<br />


==About this Structure==
==RADA Recombinase in complex with AMPPNP at pH 6.0==
2B21 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=ANP:'>ANP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B21 OCA].  
<StructureSection load='2b21' size='340' side='right'caption='[[2b21]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2b21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B21 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b21 OCA], [https://pdbe.org/2b21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b21 RCSB], [https://www.ebi.ac.uk/pdbsum/2b21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b21 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RADA_METVO RADA_METVO] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b21_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b21 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Resolvase 3D structures|Resolvase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanococcus voltae]]
[[Category: Methanococcus voltae]]
[[Category: Single protein]]
[[Category: He Y]]
[[Category: He, Y.]]
[[Category: Luo Y]]
[[Category: Luo, Y.]]
[[Category: Qian X]]
[[Category: Qian, X.]]
[[Category: Wu Y]]
[[Category: Wu, Y.]]
[[Category: ANP]]
[[Category: K]]
[[Category: MG]]
[[Category: atpase]]
[[Category: co-factors]]
[[Category: ph-dependence]]
[[Category: protein-atp complex]]
[[Category: rada/adp complex]]
 
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