2b0o: Difference between revisions

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<StructureSection load='2b0o' size='340' side='right'caption='[[2b0o]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
<StructureSection load='2b0o' size='340' side='right'caption='[[2b0o]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2b0o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B0O FirstGlance]. <br>
<table><tr><td colspan='2'>[[2b0o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B0O FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DDEFL1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b0o OCA], [https://pdbe.org/2b0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b0o RCSB], [https://www.ebi.ac.uk/pdbsum/2b0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b0o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b0o OCA], [https://pdbe.org/2b0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b0o RCSB], [https://www.ebi.ac.uk/pdbsum/2b0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b0o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ASAP3_HUMAN ASAP3_HUMAN]] Promotes cell proliferation.<ref>PMID:14654939</ref>
[https://www.uniprot.org/uniprot/ASAP3_HUMAN ASAP3_HUMAN] Promotes cell proliferation.<ref>PMID:14654939</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C]]
[[Category: Arrowsmith C]]
[[Category: Bochkarev, A]]
[[Category: Bochkarev A]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Ismail, S]]
[[Category: Ismail S]]
[[Category: Park, H]]
[[Category: Park H]]
[[Category: Structural genomic]]
[[Category: Shen L]]
[[Category: Shen, L]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M]]
[[Category: Weigelt J]]
[[Category: Weigelt, J]]
[[Category: Arfgap]]
[[Category: Metal binding protein]]
[[Category: Sgc]]

Latest revision as of 10:32, 23 August 2023

Crystal structure of UPLC1 GAP domainCrystal structure of UPLC1 GAP domain

Structural highlights

2b0o is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.06Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ASAP3_HUMAN Promotes cell proliferation.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Okabe H, Furukawa Y, Kato T, Hasegawa S, Yamaoka Y, Nakamura Y. Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas. Int J Oncol. 2004 Jan;24(1):43-8. PMID:14654939

2b0o, resolution 2.06Å

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