2ary: Difference between revisions

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OCA

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 ==Catalytic domain of Human Calpain-1==
-<StructureSection load='2ary' size='340' side='right' caption='[[2ary]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+<StructureSection load='2ary' size='340' side='right'caption='[[2ary]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2ary]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ARY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ARY FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2ary]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ARY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ARY FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAPN1, CANPL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calpain-1 Calpain-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.52 3.4.22.52] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ary FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ary OCA], [https://pdbe.org/2ary PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ary RCSB], [https://www.ebi.ac.uk/pdbsum/2ary PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ary ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ary FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ary OCA], [http://pdbe.org/2ary PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ary RCSB], [http://www.ebi.ac.uk/pdbsum/2ary PDBsum]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CAN1_HUMAN CAN1_HUMAN]] Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
+[https://www.uniprot.org/uniprot/CAN1_HUMAN CAN1_HUMAN] Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ar/2ary_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ar/2ary_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ary ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 31: / Line 31: @@
 ==See Also==
-*[[Calpain|Calpain]]
+*[[Calpain 3D structures|Calpain 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Calpain-1]]
+[[Category: Homo sapiens]]
-[[Category: Human]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C]]
+[[Category: Arrowsmith C]]
-[[Category: Bochkarev, A]]
+[[Category: Bochkarev A]]
-[[Category: Davis, T]]
+[[Category: Davis T]]
-[[Category: Dhe-Paganon, S]]
+[[Category: Dhe-Paganon S]]
-[[Category: Edwards, A]]
+[[Category: Edwards A]]
-[[Category: Lunin, V]]
+[[Category: Lunin V]]
-[[Category: Mackenzie, F]]
+[[Category: Mackenzie F]]
-[[Category: Newman, E M]]
+[[Category: Newman EM]]
-[[Category: Structural genomic]]
+[[Category: Sundstrom M]]
-[[Category: Sundstrom, M]]
+[[Category: Walker JR]]
-[[Category: Walker, J R]]
+[[Category: Weigelt J]]
-[[Category: Weigelt, J]]
-[[Category: Calcium-dependent]]
-[[Category: Cysteine protease]]
-[[Category: Hydrolase]]
-[[Category: Papain]]
-[[Category: Sgc]]
-[[Category: Thiol protease]]