2a1f: Difference between revisions

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==Crystal Structure of Uridylate kinase==
==Crystal Structure of Uridylate kinase==
<StructureSection load='2a1f' size='340' side='right' caption='[[2a1f]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2a1f' size='340' side='right'caption='[[2a1f]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2a1f]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A1F FirstGlance]. <br>
<table><tr><td colspan='2'>[[2a1f]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A1F FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrH, smbA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 "Bacterium influenzae" Lehmann and Neumann 1896])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a1f OCA], [http://pdbe.org/2a1f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2a1f RCSB], [http://www.ebi.ac.uk/pdbsum/2a1f PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2a1f TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a1f OCA], [https://pdbe.org/2a1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a1f RCSB], [https://www.ebi.ac.uk/pdbsum/2a1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a1f ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2a1f TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PYRH_HAEIN PYRH_HAEIN]] Catalyzes the reversible phosphorylation of UMP to UDP.<ref>PMID:17210578</ref>
[https://www.uniprot.org/uniprot/PYRH_HAEIN PYRH_HAEIN] Catalyzes the reversible phosphorylation of UMP to UDP.<ref>PMID:17210578</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/2a1f_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/2a1f_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a1f ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacterium influenzae lehmann and neumann 1896]]
[[Category: Haemophilus influenzae]]
[[Category: Burley, S K]]
[[Category: Large Structures]]
[[Category: Gorman, J]]
[[Category: Burley SK]]
[[Category: Structural genomic]]
[[Category: Gorman J]]
[[Category: Shapiro, L]]
[[Category: Shapiro L]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Pyrh]]
[[Category: Transferase]]
[[Category: Uridylate kinase]]

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