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==Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme==
==Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme==
<StructureSection load='1zvh' size='340' side='right' caption='[[1zvh]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='1zvh' size='340' side='right'caption='[[1zvh]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1zvh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZVH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZVH FirstGlance]. <br>
<table><tr><td colspan='2'>[[1zvh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZVH FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zv5|1zv5]], [[1zvy|1zvy]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zvh OCA], [https://pdbe.org/1zvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zvh RCSB], [https://www.ebi.ac.uk/pdbsum/1zvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zvh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zvh OCA], [http://pdbe.org/1zvh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zvh RCSB], [http://www.ebi.ac.uk/pdbsum/1zvh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zvh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zv/1zvh_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zv/1zvh_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
*[[3D structures of antibody|3D structures of antibody]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Camelus dromedarius]]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Lysozyme]]
[[Category: Large Structures]]
[[Category: Conrath, K]]
[[Category: Conrath K]]
[[Category: Decanniere, K]]
[[Category: De Genst E]]
[[Category: Genst, E De]]
[[Category: Decanniere K]]
[[Category: Kinne, J]]
[[Category: Kinne J]]
[[Category: Loris, R]]
[[Category: Loris R]]
[[Category: Muyldermans, S]]
[[Category: Muyldermans S]]
[[Category: Silence, K]]
[[Category: Silence K]]
[[Category: Wyns, L]]
[[Category: Wyns L]]
[[Category: Alpha-beta orthogonal bundle]]
[[Category: Beta sandwich]]
[[Category: Hydrolase-immune system complex]]
[[Category: Immunoglobulin fold]]
[[Category: Protein-protein heterocomplex]]

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