1zkf: Difference between revisions

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[[Image:1zkf.gif|left|200px]]


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==Cyrstal Structure of Human Cyclophilin-A in Complex with suc-AGPF-pNA==
The line below this paragraph, containing "STRUCTURE_1zkf", creates the "Structure Box" on the page.
<StructureSection load='1zkf' size='340' side='right'caption='[[1zkf]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1zkf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZKF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NIT:4-NITROANILINE'>NIT</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
{{STRUCTURE_1zkf| PDB=1zkf |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zkf OCA], [https://pdbe.org/1zkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zkf RCSB], [https://www.ebi.ac.uk/pdbsum/1zkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zkf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zk/1zkf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zkf ConSurf].
<div style="clear:both"></div>


'''Cyrstal Structure of Human Cyclophilin-A in Complex with suc-AGPF-pNA'''
==See Also==
 
*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1ZKF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZKF OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Eisenmesser EZ]]
[[Category: Eisenmesser, E Z.]]
[[Category: Kern D]]
[[Category: Kern, D.]]
[[Category: Pozharski E]]
[[Category: Pozharski, E.]]
[[Category: Thai V]]
[[Category: Thai, V.]]
[[Category: Cyclophilin]]
[[Category: Cyclophilin-a]]
[[Category: Cypa]]
[[Category: Isomerase]]
[[Category: Ppiase]]
[[Category: Prolyl-isomerase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 17:44:04 2008''

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