1th3: Difference between revisions

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-[[Image:1th3.png|left|200px]]
-{{STRUCTURE_1th3|  PDB=1th3  |  SCENE=  }}
+==Crystal structure of NADPH depleted bovine live catalase complexed with cyanide==
+<StructureSection load='1th3' size='340' side='right'caption='[[1th3]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-===Crystal structure of NADPH depleted bovine live catalase complexed with cyanide===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1th3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TH3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TH3 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-[[1th3]] is a 4 chain structure of [[Catalase]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TH3 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1th3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1th3 OCA], [https://pdbe.org/1th3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1th3 RCSB], [https://www.ebi.ac.uk/pdbsum/1th3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1th3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CATA_BOVIN CATA_BOVIN] Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/th/1th3_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1th3 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Catalase|Catalase]]
+*[[Catalase 3D structures|Catalase 3D structures]]
+__TOC__
+</StructureSection>
 [[Category: Bos taurus]]
-[[Category: Catalase]]
+[[Category: Large Structures]]
-[[Category: Balasundaresan, D.]]
+[[Category: Balasundaresan D]]
-[[Category: Kumaran, D.]]
+[[Category: Kumaran D]]
-[[Category: Ponnuswamy, M N.]]
+[[Category: Ponnuswamy MN]]
-[[Category: Sekar, K.]]
+[[Category: Sekar K]]
-[[Category: Sugadev, R.]]
+[[Category: Sugadev R]]
-[[Category: Swaminathan, S.]]
+[[Category: Swaminathan S]]
-[[Category: Bovine liver catalase]]
-[[Category: Cyanide]]
-[[Category: Nadph]]
-[[Category: Oxidoreductase]]