1t2c: Difference between revisions
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==Plasmodium falciparum lactate dehydrogenase complexed with NADH== | ==Plasmodium falciparum lactate dehydrogenase complexed with NADH== | ||
<StructureSection load='1t2c' size='340' side='right' caption='[[1t2c]], [[Resolution|resolution]] 2.01Å' scene=''> | <StructureSection load='1t2c' size='340' side='right'caption='[[1t2c]], [[Resolution|resolution]] 2.01Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1t2c]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1t2c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T2C FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr> | |||
<tr><td class="sblockLbl"><b>[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t2c OCA], [https://pdbe.org/1t2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t2c RCSB], [https://www.ebi.ac.uk/pdbsum/1t2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t2c ProSAT]</span></td></tr> | ||
</table> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | == Function == | ||
<table> | [https://www.uniprot.org/uniprot/LDH_PLAFD LDH_PLAFD] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t2/1t2c_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t2/1t2c_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t2c ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 1t2c" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
*[[Lactate | *[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
[[Category: Barros | [[Category: Barros D]] | ||
[[Category: Brady | [[Category: Brady RL]] | ||
[[Category: Cameron | [[Category: Cameron A]] | ||
[[Category: Croft | [[Category: Croft SL]] | ||
[[Category: Easton | [[Category: De Las Heras FG]] | ||
[[Category: Gabarro | [[Category: Easton A]] | ||
[[Category: Gamo | [[Category: Gabarro R]] | ||
[[Category: Garcia-Ochoa | [[Category: Gamo FJ]] | ||
[[Category: Garcia-Ochoa S]] | |||
[[Category: Kendrick | [[Category: Kendrick H]] | ||
[[Category: Lavandera | [[Category: Lavandera JL]] | ||
[[Category: Leon | [[Category: Leon L]] | ||
[[Category: Mallo | [[Category: Mallo A]] | ||
[[Category: Martin | [[Category: Martin JJ]] | ||
[[Category: Read | [[Category: Read J]] | ||
[[Category: Risco | [[Category: Risco F]] | ||
[[Category: Ruiz | [[Category: Ruiz JR]] | ||
[[Category: Sanz | [[Category: Sanz L]] | ||
[[Category: Sessions | [[Category: Sessions RB]] | ||
[[Category: Tranter | [[Category: Tranter R]] | ||
[[Category: Vivas | [[Category: Vivas L]] | ||
[[Category: Winter | [[Category: Winter VJ]] | ||