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==Crystal structure of human GDP-D-mannose 4,6-dehydratase== | ==Crystal structure of human GDP-D-mannose 4,6-dehydratase== | ||
<StructureSection load='1t2a' size='340' side='right' caption='[[1t2a]], [[Resolution|resolution]] 1.84Å' scene=''> | <StructureSection load='1t2a' size='340' side='right'caption='[[1t2a]], [[Resolution|resolution]] 1.84Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1t2a]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1t2a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T2A FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t2a OCA], [https://pdbe.org/1t2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t2a RCSB], [https://www.ebi.ac.uk/pdbsum/1t2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t2a ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GMDS_HUMAN GMDS_HUMAN] Conversion of GDP-D-mannose to GDP-4-keto-6-D-deoxymannose. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith C]] | ||
[[Category: Edwards | [[Category: Edwards A]] | ||
[[Category: Houston | [[Category: Houston S]] | ||
[[Category: Loppnau | [[Category: Loppnau P]] | ||
[[Category: Oppermann | [[Category: Oppermann U]] | ||
[[Category: Sharma | [[Category: Sharma S]] | ||
[[Category: Sundstrom | [[Category: Sundstrom M]] | ||
[[Category: Vedadi | [[Category: Vedadi M]] | ||
[[Category: Walker | [[Category: Walker JR]] | ||
[[Category: Wasney | [[Category: Wasney G]] | ||
Latest revision as of 09:23, 23 August 2023
Crystal structure of human GDP-D-mannose 4,6-dehydrataseCrystal structure of human GDP-D-mannose 4,6-dehydratase
Structural highlights
FunctionGMDS_HUMAN Conversion of GDP-D-mannose to GDP-4-keto-6-D-deoxymannose. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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