1si8: Difference between revisions

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-{{Seed}}
-[[Image:1si8.png|left|200px]]
-<!--
+==Crystal structure of E. faecalis catalase==
-The line below this paragraph, containing "STRUCTURE_1si8", creates the "Structure Box" on the page.
+<StructureSection load='1si8' size='340' side='right'caption='[[1si8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1si8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_V583 Enterococcus faecalis V583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SI8 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_1si8|  PDB=1si8  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1si8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1si8 OCA], [https://pdbe.org/1si8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1si8 RCSB], [https://www.ebi.ac.uk/pdbsum/1si8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1si8 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q834P5_ENTFA Q834P5_ENTFA]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/si/1si8_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1si8 ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Enterococcus faecalis haem catalase was crystallized using lithium sulfate at neutral pH. The crystals belong to space group R3, with unit-cell parameters a = b = 236.9, c = 198.1 A. The three-dimensional structure was determined by molecular replacement using a subunit of the Proteus mirabilis catalase structure. It was refined against 2.3 A synchrotron data to a free R factor of 21.8%. Like other catalases, the E. faecalis catalase is a homotetramer with a fold and structure similar to those of its structurally closest relative P. mirabilis. The solvent structure in the active site is identical in the four subunits but differs from that found in other catalases. The structural consequences of the Ramachandran outlier Ser196 are discussed.
-===Crystal structure of E. faecalis catalase===
+The three-dimensional structure of catalase from Enterococcus faecalis.,Hakansson KO, Brugna M, Tasse L Acta Crystallogr D Biol Crystallogr. 2004 Aug;60(Pt 8):1374-80. Epub 2004, Jul 21. PMID:15272159<ref>PMID:15272159</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 1si8" style="background-color:#fffaf0;"></div>
-<!--
+==See Also==
-The line below this paragraph, {{ABSTRACT_PUBMED_15272159}}, adds the Publication Abstract to the page
+*[[Catalase 3D structures|Catalase 3D structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 15272159 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_15272159}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Enterococcus faecalis V583]]
-SI8 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SI8 OCA].
+[[Category: Large Structures]]
+[[Category: Brugna M]]
-==Reference==
+[[Category: Hakansson KO]]
-<ref group="xtra">PMID:15272159</ref><references group="xtra"/>
+[[Category: Tasse L]]
-[[Category: Catalase]]
-[[Category: Enterococcus faecalis]]
-[[Category: Brugna, M.]]
-[[Category: Hakansson, K O.]]
-[[Category: Tasse, L.]]
-[[Category: Anti-parallel beta-barrel]]
-[[Category: C-terminal helical region]]
-[[Category: Heme group]]
-[[Category: N-terminal arm]]
-[[Category: Tetramer]]
-[[Category: Wrapping region]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:12:15 2009''