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[[Image:1ryz.jpg|left|200px]]


{{Structure
==Uridine Phosphorylase from Salmonella typhimurium. Crystal Structure at 2.9 A Resolution==
|PDB= 1ryz |SIZE=350|CAPTION= <scene name='initialview01'>1ryz</scene>, resolution 2.90&Aring;
<StructureSection load='1ryz' size='340' side='right'caption='[[1ryz]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>
<table><tr><td colspan='2'>[[1ryz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RYZ FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
|GENE= udp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=602 Salmonella typhimurium])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ryz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ryz OCA], [https://pdbe.org/1ryz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ryz RCSB], [https://www.ebi.ac.uk/pdbsum/1ryz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ryz ProSAT]</span></td></tr>
|RELATEDENTRY=[[1k3f|1K3F]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ryz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ryz OCA], [http://www.ebi.ac.uk/pdbsum/1ryz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ryz RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ry/1ryz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ryz ConSurf].
<div style="clear:both"></div>


'''Uridine Phosphorylase from Salmonella typhimurium. Crystal Structure at 2.9 A Resolution'''
==See Also==
 
*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1RYZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RYZ OCA].
[[Category: Large Structures]]
[[Category: Salmonella typhimurium]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Single protein]]
[[Category: Dontsova MV]]
[[Category: Uridine phosphorylase]]
[[Category: Ealick SE]]
[[Category: Dontsova, M V.]]
[[Category: Gabdoulkhakov AG]]
[[Category: Ealick, S E.]]
[[Category: Lyashenko AV]]
[[Category: Gabdoulkhakov, A G.]]
[[Category: Mikhailov AM]]
[[Category: Lyashenko, A V.]]
[[Category: Nikonov SV]]
[[Category: Mikhailov, A M.]]
[[Category: Nikonov, S V.]]
[[Category: nucleoside phosphorylase]]
[[Category: uridine phosphorylase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:34:58 2008''

Latest revision as of 09:09, 23 August 2023

Uridine Phosphorylase from Salmonella typhimurium. Crystal Structure at 2.9 A ResolutionUridine Phosphorylase from Salmonella typhimurium. Crystal Structure at 2.9 A Resolution

Structural highlights

1ryz is a 6 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UDP_SALTY Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1ryz, resolution 2.90Å

Drag the structure with the mouse to rotate

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