1ryz: Difference between revisions

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[[Image:1ryz.jpg|left|200px]]<br /><applet load="1ryz" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1ryz, resolution 2.90&Aring;" />
'''Uridine Phosphorylase from Salmonella typhimurium. Crystal Structure at 2.9 A Resolution'''<br />


==About this Structure==
==Uridine Phosphorylase from Salmonella typhimurium. Crystal Structure at 2.9 A Resolution==
1RYZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RYZ OCA].
<StructureSection load='1ryz' size='340' side='right'caption='[[1ryz]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
[[Category: Salmonella typhimurium]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1ryz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RYZ FirstGlance]. <br>
[[Category: Uridine phosphorylase]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
[[Category: Dontsova, M V.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene></td></tr>
[[Category: Ealick, S E.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ryz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ryz OCA], [https://pdbe.org/1ryz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ryz RCSB], [https://www.ebi.ac.uk/pdbsum/1ryz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ryz ProSAT]</span></td></tr>
[[Category: Gabdoulkhakov, A G.]]
</table>
[[Category: Lyashenko, A V.]]
== Function ==
[[Category: Mikhailov, A M.]]
[https://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).
[[Category: Nikonov, S V.]]
== Evolutionary Conservation ==
[[Category: ACY]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: nucleoside phosphorylase]]
Check<jmol>
[[Category: uridine phosphorylase]]
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ry/1ryz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ryz ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:56:04 2008''
==See Also==
*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Dontsova MV]]
[[Category: Ealick SE]]
[[Category: Gabdoulkhakov AG]]
[[Category: Lyashenko AV]]
[[Category: Mikhailov AM]]
[[Category: Nikonov SV]]

Latest revision as of 09:09, 23 August 2023

Uridine Phosphorylase from Salmonella typhimurium. Crystal Structure at 2.9 A ResolutionUridine Phosphorylase from Salmonella typhimurium. Crystal Structure at 2.9 A Resolution

Structural highlights

1ryz is a 6 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UDP_SALTY Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1ryz, resolution 2.90Å

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