5hz0: Difference between revisions

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'''Unreleased structure'''


The entry 5hz0 is ON HOLD
==Plant peptide hormone receptor RGFR1 in complex with RGF2==
 
<StructureSection load='5hz0' size='340' side='right'caption='[[5hz0]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
Authors: Songwen, Hanzhifu, Chaijijie
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5hz0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis Arabidopsis] and [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HZ0 FirstGlance]. <br>
Description: Plant Receptor
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HZP:(4S)-4-HYDROXY-L-PROLINE'>HZP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
[[Category: Songwen, Hanzhifu, Chaijijie]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hz0 OCA], [https://pdbe.org/5hz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hz0 RCSB], [https://www.ebi.ac.uk/pdbsum/5hz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hz0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RGI3_ARATH RGI3_ARATH] Together with RGI1, RGI2, RGI4 and RGI5, acts as receptor of RGF peptides (e.g. RGF1, GLV5/CLEL1/RGF2, GLV7/CLEL3/RGF3, GLV3/RGF4, GLV10/CLEL7/RGF5 and RGF10/CLELN), peptide hormones which maintain the postembryonic root stem cell niche by regulating the expression levels and patterns of the transcription factor PLETHORA (PLT, e.g. PLT1 and PLT2) (PubMed:27229311, PubMed:27229312, PubMed:27001831). Links RGF peptides signal with their downstream components (PubMed:27229311, PubMed:27001831).<ref>PMID:27001831</ref> <ref>PMID:27229311</ref> <ref>PMID:27229312</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis]]
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Chai J]]
[[Category: Han Z]]
[[Category: Song W]]

Latest revision as of 14:00, 16 August 2023

Plant peptide hormone receptor RGFR1 in complex with RGF2Plant peptide hormone receptor RGFR1 in complex with RGF2

Structural highlights

5hz0 is a 2 chain structure with sequence from Arabidopsis and Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.56Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RGI3_ARATH Together with RGI1, RGI2, RGI4 and RGI5, acts as receptor of RGF peptides (e.g. RGF1, GLV5/CLEL1/RGF2, GLV7/CLEL3/RGF3, GLV3/RGF4, GLV10/CLEL7/RGF5 and RGF10/CLELN), peptide hormones which maintain the postembryonic root stem cell niche by regulating the expression levels and patterns of the transcription factor PLETHORA (PLT, e.g. PLT1 and PLT2) (PubMed:27229311, PubMed:27229312, PubMed:27001831). Links RGF peptides signal with their downstream components (PubMed:27229311, PubMed:27001831).[1] [2] [3]

References

  1. ↑ Shinohara H, Mori A, Yasue N, Sumida K, Matsubayashi Y. Identification of three LRR-RKs involved in perception of root meristem growth factor in Arabidopsis. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):3897-902. PMID:27001831 doi:10.1073/pnas.1522639113
  2. ↑ Song W, Liu L, Wang J, Wu Z, Zhang H, Tang J, Lin G, Wang Y, Wen X, Li W, Han Z, Guo H, Chai J. Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth. Cell Res. 2016 Jun;26(6):674-85. doi: 10.1038/cr.2016.62. Epub 2016 May 27. PMID:27229311 doi:http://dx.doi.org/10.1038/cr.2016.62
  3. ↑ Ou Y, Lu X, Zi Q, Xun Q, Zhang J, Wu Y, Shi H, Wei Z, Zhao B, Zhang X, He K, Gou X, Li C, Li J. RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor 1 in Arabidopsis thaliana. Cell Res. 2016 Jun;26(6):686-98. PMID:27229312 doi:10.1038/cr.2016.63

5hz0, resolution 2.56Å

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