5hu4: Difference between revisions

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 <StructureSection load='5hu4' size='340' side='right'caption='[[5hu4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5hu4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HU4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HU4 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5hu4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HU4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HU4 FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ABE86_07720, ABE87_06300, AMC92_10805, ARD00_01217 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1639 "Bacterium monocytogenes hominis" Nyfeldt 1932])</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hu4 OCA], [http://pdbe.org/5hu4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hu4 RCSB], [http://www.ebi.ac.uk/pdbsum/5hu4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hu4 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hu4 OCA], [https://pdbe.org/5hu4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hu4 RCSB], [https://www.ebi.ac.uk/pdbsum/5hu4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hu4 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/SRTA_LISMO SRTA_LISMO] Transpeptidase that anchors surface proteins to the cell wall (PubMed:11854224, PubMed:11929538, PubMed:16247833, PubMed:22837151). Recognizes and modifies its substrate by proteolytic cleavage of a C-terminal sorting signal. Following cleavage, a covalent intermediate is formed via a thioester bond between the sortase and its substrate, which is then transferred and covalently attached to the cell wall (Probable). This sortase recognizes a Leu-Pro-x-Thr-Gly (LPXTG) motif, which is cleaved by the sortase between the threonine and glycine residues (PubMed:11929538). Involved in pathogenesis (PubMed:11854224, PubMed:11929538, PubMed:15028680). May regulate the rate of synthesis and/or the stability of a subset of LPXTG proteins (PubMed:22837151). Not involved in cell wall-anchoring of Hbp2 (SvpA) or Hbp1 (PubMed:15028680, PubMed:16247833).<ref>PMID:11854224</ref> <ref>PMID:11929538</ref> <ref>PMID:15028680</ref> <ref>PMID:16247833</ref> <ref>PMID:22837151</ref> <ref>PMID:11929538</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 __TOC__
 </StructureSection>
-[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]
 [[Category: Large Structures]]
-[[Category: Li, H]]
+[[Category: Listeria monocytogenes]]
-[[Category: Hydrolase]]
+[[Category: Li H]]
-[[Category: Protease]]
-[[Category: Sortase some]]