5hob: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 5hob is ON HOLD  until Paper Publication
+==p73 homo-tetramerization domain mutant I==
+<StructureSection load='5hob' size='340' side='right'caption='[[5hob]], [[Resolution|resolution]] 1.22&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5hob]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HOB FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.220013&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hob OCA], [https://pdbe.org/5hob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hob RCSB], [https://www.ebi.ac.uk/pdbsum/5hob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hob ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>
-Authors:
+==See Also==
+*[[P73|P73]]
-Description:
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Coutandin D]]
+[[Category: Dotsch V]]
+[[Category: Knapp S]]
+[[Category: Krojer T]]
+[[Category: Mathea S]]
+[[Category: Salah E]]