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==2.85 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Adenosine and NAD.==
==2.85 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Adenosine and NAD.==
<StructureSection load='5hm8' size='340' side='right' caption='[[5hm8]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
<StructureSection load='5hm8' size='340' side='right'caption='[[5hm8]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5hm8]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HM8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HM8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5hm8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HM8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteinase Adenosylhomocysteinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.1.1 3.3.1.1] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hm8 OCA], [http://pdbe.org/5hm8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hm8 RCSB], [http://www.ebi.ac.uk/pdbsum/5hm8 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hm8 OCA], [https://pdbe.org/5hm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hm8 RCSB], [https://www.ebi.ac.uk/pdbsum/5hm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hm8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5CPH1_CRYPI Q5CPH1_CRYPI]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Adenosylhomocysteinase]]
[[Category: Cryptosporidium parvum Iowa II]]
[[Category: Anderson, W F]]
[[Category: Large Structures]]
[[Category: Bishop, B]]
[[Category: Anderson WF]]
[[Category: Structural genomic]]
[[Category: Bishop B]]
[[Category: Dubrovska, I]]
[[Category: Dubrovska I]]
[[Category: Halavaty, A]]
[[Category: Halavaty A]]
[[Category: Kiryukhina, O]]
[[Category: Kiryukhina O]]
[[Category: Kwon, K]]
[[Category: Kwon K]]
[[Category: Minasov, G]]
[[Category: Minasov G]]
[[Category: Shuvalova, L]]
[[Category: Shuvalova L]]
[[Category: Adenosine]]
[[Category: Csgid]]
[[Category: Hydrolase]]
[[Category: Nad]]
[[Category: S-adenosylhomocysteinase]]

Latest revision as of 13:46, 16 August 2023

2.85 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Adenosine and NAD.2.85 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Adenosine and NAD.

Structural highlights

5hm8 is a 8 chain structure with sequence from Cryptosporidium parvum Iowa II. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.85Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q5CPH1_CRYPI

5hm8, resolution 2.85Å

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OCA