2xda: Difference between revisions

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[[Image:2xda.jpg|left|200px]]


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==STRUCTURE OF HELICOBACTER PYLORI TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (4R,6R,7S)-2-(2-Cyclopropyl)ethyl-4,6,7- trihydroxy-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid==
The line below this paragraph, containing "STRUCTURE_2xda", creates the "Structure Box" on the page.
<StructureSection load='2xda' size='340' side='right'caption='[[2xda]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2xda]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XDA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XDA FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JPS:(4R,6R,7S)-2-(2-CYCLOPROPYLETHYL)-4,6,7-TRIHYDROXY-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-4-CARBOXYLIC+ACID'>JPS</scene></td></tr>
{{STRUCTURE_2xda|  PDB=2xda  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xda OCA], [https://pdbe.org/2xda PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xda RCSB], [https://www.ebi.ac.uk/pdbsum/2xda PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xda ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROQ_HELPY AROQ_HELPY] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]


===STRUCTURE OF HELICOBACTER PYLORI TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (4R,6R,7S)-2-(2-CYCLOPROPYL)ETHYL-4,6,7-TRIHYDROXY-4,5,6,7-TETRAHYDROBENZO(B)THIOPHENE-4-CARBOXYLIC ACID===
==See Also==
 
*[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2XDA is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XDA OCA].
 
==Reference==
<ref group="xtra">PMID:21069655</ref><references group="xtra"/>
[[Category: 3-dehydroquinate dehydratase]]
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
[[Category: Castedo, L.]]
[[Category: Large Structures]]
[[Category: Fox, G C.]]
[[Category: Castedo L]]
[[Category: Gonzalez-Bello, C.]]
[[Category: Fox GC]]
[[Category: Hawkins, A R.]]
[[Category: Gonzalez-Bello C]]
[[Category: Lamb, H.]]
[[Category: Hawkins AR]]
[[Category: Llamas-Saiz, A L.]]
[[Category: Lamb H]]
[[Category: Otero, J M.]]
[[Category: Llamas-Saiz AL]]
[[Category: Paz, S.]]
[[Category: Otero JM]]
[[Category: Raaij, M J.Van.]]
[[Category: Paz S]]
[[Category: Tizon, L.]]
[[Category: Tizon L]]
[[Category: Aromatic amino acid biosynthesis]]
[[Category: Van Raaij MJ]]
[[Category: Lyase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 14:10:43 2010''

Latest revision as of 13:38, 16 August 2023

STRUCTURE OF HELICOBACTER PYLORI TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (4R,6R,7S)-2-(2-Cyclopropyl)ethyl-4,6,7- trihydroxy-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acidSTRUCTURE OF HELICOBACTER PYLORI TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (4R,6R,7S)-2-(2-Cyclopropyl)ethyl-4,6,7- trihydroxy-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid

Structural highlights

2xda is a 1 chain structure with sequence from Helicobacter pylori. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AROQ_HELPY Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]

See Also

2xda, resolution 1.85Å

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