4ow3: Difference between revisions

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-'''Unreleased structure'''
-The entry 4ow3 is ON HOLD
+==Thermolysin structure determined by free-electron laser==
+<StructureSection load='4ow3' size='340' side='right'caption='[[4ow3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4ow3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OW3 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ow3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ow3 OCA], [https://pdbe.org/4ow3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ow3 RCSB], [https://www.ebi.ac.uk/pdbsum/4ow3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ow3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+X-ray free-electron laser (XFEL) sources enable the use of crystallography to solve three-dimensional macromolecular structures under native conditions and without radiation damage. Results to date, however, have been limited by the challenge of deriving accurate Bragg intensities from a heterogeneous population of microcrystals, while at the same time modeling the X-ray spectrum and detector geometry. Here we present a computational approach designed to extract meaningful high-resolution signals from fewer diffraction measurements.
-Authors: Hattne, J., Echols, N., Tran, R., Kern, J., Gildea, R.J., Brewster, A.S., Alonso-Mori, R., Glockner, C., Hellmich, J., Laksmono, H., Sierra, R.G., Lassalle-Kaiser, B., Lampe, A., Han, G., Gul, S., DiFiore, D., Milathianaki, D., Fry, A.R., Miahnahri, A., White, W.E., Schafer, D.W., Seibert, M.M., Koglin, J.E., Sokaras, D., Weng, T.-C., Sellberg, J., Latimer, M.J., Glatzel, P., Zwart, P.H., Grosse-Kunstleve, R.W., Bogan, M.J., Messerschmidt, M., Williams, G.J., Boutet, S., Messinger, J., Zouni, A., Yano, J., Bergmann, U., Yachandra, V.K., Adams, P.D., Sauter, N.K.
+Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers.,Hattne J, Echols N, Tran R, Kern J, Gildea RJ, Brewster AS, Alonso-Mori R, Glockner C, Hellmich J, Laksmono H, Sierra RG, Lassalle-Kaiser B, Lampe A, Han G, Gul S, DiFiore D, Milathianaki D, Fry AR, Miahnahri A, White WE, Schafer DW, Seibert MM, Koglin JE, Sokaras D, Weng TC, Sellberg J, Latimer MJ, Glatzel P, Zwart PH, Grosse-Kunstleve RW, Bogan MJ, Messerschmidt M, Williams GJ, Boutet S, Messinger J, Zouni A, Yano J, Bergmann U, Yachandra VK, Adams PD, Sauter NK Nat Methods. 2014 May;11(5):545-8. doi: 10.1038/nmeth.2887. Epub 2014 Mar 16. PMID:24633409<ref>PMID:24633409</ref>
-Description: Thermolysin structure determined by free-electron laser
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 4ow3" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Thermolysin 3D structures|Thermolysin 3D structures]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Bacillus thermoproteolyticus]]
+[[Category: Large Structures]]
+[[Category: Adams PD]]
+[[Category: Alonso-Mori R]]
+[[Category: Bergmann U]]
+[[Category: Bogan MJ]]
+[[Category: Boutet S]]
+[[Category: Brewster AS]]
+[[Category: DiFiore D]]
+[[Category: Echols N]]
+[[Category: Fry AR]]
+[[Category: Gildea RJ]]
+[[Category: Glatzel P]]
+[[Category: Glockner C]]
+[[Category: Grosse-Kunstleve RW]]
+[[Category: Gul S]]
+[[Category: Han G]]
+[[Category: Hattne J]]
+[[Category: Hellmich J]]
+[[Category: Kern J]]
+[[Category: Koglin JE]]
+[[Category: Laksmono H]]
+[[Category: Lampe A]]
+[[Category: Lassalle-Kaiser B]]
+[[Category: Latimer MJ]]
+[[Category: Messerschmidt M]]
+[[Category: Messinger J]]
+[[Category: Miahnahri A]]
+[[Category: Milathianaki D]]
+[[Category: Sauter NK]]
+[[Category: Schafer DW]]
+[[Category: Seibert MM]]
+[[Category: Sellberg J]]
+[[Category: Sierra RG]]
+[[Category: Sokaras D]]
+[[Category: Tran R]]
+[[Category: Weng T-C]]
+[[Category: White WE]]
+[[Category: Williams GJ]]
+[[Category: Yachandra VK]]
+[[Category: Yano J]]
+[[Category: Zouni A]]
+[[Category: Zwart PH]]