1q5u: Difference between revisions

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<StructureSection load='1q5u' size='340' side='right'caption='[[1q5u]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1q5u' size='340' side='right'caption='[[1q5u]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1q5u]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q5U OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1Q5U FirstGlance]. <br>
<table><tr><td colspan='2'>[[1q5u]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q5U FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1q5h|1q5h]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HDUT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q5u OCA], [https://pdbe.org/1q5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q5u RCSB], [https://www.ebi.ac.uk/pdbsum/1q5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q5u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1q5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q5u OCA], [http://pdbe.org/1q5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1q5u RCSB], [http://www.ebi.ac.uk/pdbsum/1q5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1q5u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DUT_HUMAN DUT_HUMAN]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.<ref>PMID:8805593</ref>
[https://www.uniprot.org/uniprot/DUT_HUMAN DUT_HUMAN] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.<ref>PMID:8805593</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Harris, J M]]
[[Category: Harris JM]]
[[Category: Mcintosh, E M]]
[[Category: Mcintosh EM]]
[[Category: Mol, C D]]
[[Category: Mol CD]]
[[Category: Tainer, J A]]
[[Category: Tainer JA]]
[[Category: Dna repair]]
[[Category: Enzyme-dna interaction]]
[[Category: Hydrolase]]

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