1ppy: Difference between revisions

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==Native precursor of pyruvoyl dependent Aspartate decarboxylase==
==Native precursor of pyruvoyl dependent Aspartate decarboxylase==
<StructureSection load='1ppy' size='340' side='right' caption='[[1ppy]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='1ppy' size='340' side='right'caption='[[1ppy]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ppy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PPY FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ppy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PPY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aw8|1aw8]], [[1pqe|1pqe]], [[1pqf|1pqf]], [[1pqh|1pqh]], [[1pt0|1pt0]], [[1pt1|1pt1]], [[1pyq|1pyq]], [[1pyu|1pyu]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ppy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ppy OCA], [https://pdbe.org/1ppy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ppy RCSB], [https://www.ebi.ac.uk/pdbsum/1ppy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ppy ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PAND OR B0131 OR C0160 OR Z0142 OR ECS0135 OR SF0128 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate_1-decarboxylase Aspartate 1-decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.11 4.1.1.11] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ppy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ppy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ppy RCSB], [http://www.ebi.ac.uk/pdbsum/1ppy PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PAND_ECOLI PAND_ECOLI]] Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.<ref>PMID:6767707</ref>
[https://www.uniprot.org/uniprot/PAND_ECOLI PAND_ECOLI] Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.<ref>PMID:6767707</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pp/1ppy_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pp/1ppy_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ppy ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1ppy" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Aspartate decarboxylase|Aspartate decarboxylase]]
*[[Aspartate decarboxylase 3D structures|Aspartate decarboxylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aspartate 1-decarboxylase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Abell, C]]
[[Category: Large Structures]]
[[Category: Blundell, T L]]
[[Category: Abell C]]
[[Category: Chirgadze, D Y]]
[[Category: Blundell TL]]
[[Category: Kilkenny, M L]]
[[Category: Chirgadze DY]]
[[Category: Lobley, C M.C]]
[[Category: Kilkenny ML]]
[[Category: Matak-Vinkovic, D]]
[[Category: Lobley CMC]]
[[Category: Schmitzberger, F]]
[[Category: Matak-Vinkovic D]]
[[Category: Smith, A G]]
[[Category: Schmitzberger F]]
[[Category: Vinkovic, M]]
[[Category: Smith AG]]
[[Category: Webb, M E]]
[[Category: Vinkovic M]]
[[Category: Witty, M]]
[[Category: Webb ME]]
[[Category: Decarboxylase]]
[[Category: Witty M]]
[[Category: Intramolecular protein self-processing]]
[[Category: Lyase]]
[[Category: Pantothenate pathway]]

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