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==Crystal structure of KDO8P synthase in its binary complex with substrate analog E-FPEP== | ==Crystal structure of KDO8P synthase in its binary complex with substrate analog E-FPEP== | ||
<StructureSection load='1phq' size='340' side='right' caption='[[1phq]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='1phq' size='340' side='right'caption='[[1phq]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1phq]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1phq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PHQ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FPE:3-FLUORO-2-(PHOSPHONOOXY)PROPANOIC+ACID'>FPE</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1phq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1phq OCA], [https://pdbe.org/1phq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1phq RCSB], [https://www.ebi.ac.uk/pdbsum/1phq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1phq ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/KDSA_ECOLI KDSA_ECOLI] Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth.[HAMAP-Rule:MF_00056] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1phq ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1phq ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | |||
*[[Kdo-8-phosphate synthase|Kdo-8-phosphate synthase]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Adir | [[Category: Adir N]] | ||
[[Category: Baasov | [[Category: Baasov T]] | ||
[[Category: Belakhov | [[Category: Belakhov V]] | ||
[[Category: Rabkin | [[Category: Rabkin E]] | ||
[[Category: Vainer | [[Category: Vainer R]] | ||
Latest revision as of 12:43, 16 August 2023
Crystal structure of KDO8P synthase in its binary complex with substrate analog E-FPEPCrystal structure of KDO8P synthase in its binary complex with substrate analog E-FPEP
Structural highlights
FunctionKDSA_ECOLI Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth.[HAMAP-Rule:MF_00056] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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