1ooq: Difference between revisions
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<StructureSection load='1ooq' size='340' side='right'caption='[[1ooq]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1ooq' size='340' side='right'caption='[[1ooq]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ooq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1ooq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OOQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OOQ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTC:BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE]'>DTC</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ooq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ooq OCA], [https://pdbe.org/1ooq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ooq RCSB], [https://www.ebi.ac.uk/pdbsum/1ooq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ooq ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ooq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ooq OCA], [https://pdbe.org/1ooq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ooq RCSB], [https://www.ebi.ac.uk/pdbsum/1ooq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ooq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/NFSB_ECOLI NFSB_ECOLI] Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.<ref>PMID:15684426</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Nitroreductase|Nitroreductase]] | *[[Nitroreductase 3D structures|Nitroreductase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Denny | [[Category: Denny WA]] | ||
[[Category: Johansson | [[Category: Johansson E]] | ||
[[Category: Neidle | [[Category: Neidle S]] | ||
[[Category: Parkinson | [[Category: Parkinson GN]] | ||