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==OUTER MEMBRANE COBALAMIN TRANSPORTER (BTUB) FROM E. COLI==
==OUTER MEMBRANE COBALAMIN TRANSPORTER (BTUB) FROM E. COLI==
<StructureSection load='1nqe' size='340' side='right' caption='[[1nqe]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1nqe' size='340' side='right'caption='[[1nqe]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1nqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NQE FirstGlance]. <br>
<table><tr><td colspan='2'>[[1nqe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NQE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nqf|1nqf]], [[1nqg|1nqg]], [[1nqh|1nqh]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">btuB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nqe OCA], [https://pdbe.org/1nqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nqe RCSB], [https://www.ebi.ac.uk/pdbsum/1nqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nqe ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nqe OCA], [http://pdbe.org/1nqe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nqe RCSB], [http://www.ebi.ac.uk/pdbsum/1nqe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nqe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BTUB_ECOLI BTUB_ECOLI]] Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Is also a receptor for bacteriophages BF23 and C1, and for A and E colicins.[HAMAP-Rule:MF_01531]  
[https://www.uniprot.org/uniprot/BTUB_ECOLI BTUB_ECOLI] Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Is also a receptor for bacteriophages BF23 and C1, and for A and E colicins.[HAMAP-Rule:MF_01531]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1nqe" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1nqe" style="background-color:#fffaf0;"></div>
==See Also==
*[[BtuB 3D structures|BtuB 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Chimento, D P]]
[[Category: Large Structures]]
[[Category: Kadner, R J]]
[[Category: Chimento DP]]
[[Category: Mohanty, A K]]
[[Category: Kadner RJ]]
[[Category: Wiener, M C]]
[[Category: Mohanty AK]]
[[Category: Beta barrel]]
[[Category: Wiener MC]]
[[Category: Cobalamin]]
[[Category: Outer membrane transport]]
[[Category: Transport protein]]
[[Category: Vitamin b12]]

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