1lm6: Difference between revisions

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<StructureSection load='1lm6' size='340' side='right'caption='[[1lm6]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='1lm6' size='340' side='right'caption='[[1lm6]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1lm6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplococcus_pneumoniae"_(klein_1884)_weichselbaum_1886 "diplococcus pneumoniae" (klein 1884) weichselbaum 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LM6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LM6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1lm6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LM6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lm4|1lm4]], [[1lme|1lme]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lm6 OCA], [https://pdbe.org/1lm6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lm6 RCSB], [https://www.ebi.ac.uk/pdbsum/1lm6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lm6 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lm6 OCA], [http://pdbe.org/1lm6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1lm6 RCSB], [http://www.ebi.ac.uk/pdbsum/1lm6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1lm6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DEF_STRPN DEF_STRPN]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).  
[https://www.uniprot.org/uniprot/DEF_STRPN DEF_STRPN] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Peptide deformylase]]
[[Category: Streptococcus pneumoniae]]
[[Category: Ericson, C]]
[[Category: Ericson C]]
[[Category: Klock, H]]
[[Category: Klock H]]
[[Category: Kreusch, A]]
[[Category: Kreusch A]]
[[Category: Lee, C C]]
[[Category: Lee CC]]
[[Category: Lesley, S A]]
[[Category: Lesley SA]]
[[Category: McMullan, D]]
[[Category: McMullan D]]
[[Category: Ng, K]]
[[Category: Ng K]]
[[Category: Shin, T]]
[[Category: Shin T]]
[[Category: Spraggon, G]]
[[Category: Spraggon G]]
[[Category: Vincent, J]]
[[Category: Vincent J]]
[[Category: Warner, I]]
[[Category: Warner I]]
[[Category: Hydrolase]]
[[Category: Metalloenzyme]]
[[Category: Pdf]]

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