1kpu: Difference between revisions

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[[Image:1kpu.jpg|left|200px]]


{{Structure
==High resolution crystal structure of the MHC class I complex H-2Kb/VSV8==
|PDB= 1kpu |SIZE=350|CAPTION= <scene name='initialview01'>1kpu</scene>, resolution 1.50&Aring;
<StructureSection load='1kpu' size='340' side='right'caption='[[1kpu]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>
<table><tr><td colspan='2'>[[1kpu]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Vesicular_stomatitis_Indiana_virus Vesicular stomatitis Indiana virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KPU FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kpu OCA], [https://pdbe.org/1kpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kpu RCSB], [https://www.ebi.ac.uk/pdbsum/1kpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kpu ProSAT]</span></td></tr>
|RELATEDENTRY=[[2vaa|2vaa]], [[1kpv|1KPV]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kpu OCA], [http://www.ebi.ac.uk/pdbsum/1kpu PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1kpu RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/HA1B_MOUSE HA1B_MOUSE] Involved in the presentation of foreign antigens to the immune system.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kp/1kpu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kpu ConSurf].
<div style="clear:both"></div>


'''High resolution crystal structure of the MHC class I complex H-2Kb/VSV8'''
==See Also==
 
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
 
*[[MHC 3D structures|MHC 3D structures]]
==About this Structure==
*[[MHC I 3D structures|MHC I 3D structures]]
1KPU is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KPU OCA].
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Vesicular stomatitis Indiana virus]]
[[Category: Rudolph, M G.]]
[[Category: Rudolph MG]]
[[Category: Wilson, I A.]]
[[Category: Wilson IA]]
[[Category: major histocompatibility complex]]
[[Category: peptide-mhc]]
 
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