1kew: Difference between revisions

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<StructureSection load='1kew' size='340' side='right'caption='[[1kew]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='1kew' size='340' side='right'caption='[[1kew]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1kew]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KEW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1KEW FirstGlance]. <br>
<table><tr><td colspan='2'>[[1kew]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KEW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TYD:THYMIDINE-5-DIPHOSPHATE'>TYD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1kep|1kep]], [[1ker|1ker]], [[1ket|1ket]], [[1keu|1keu]], [[1g1a|1g1a]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TYD:THYMIDINE-5-DIPHOSPHATE'>TYD</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rmlB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kew OCA], [https://pdbe.org/1kew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kew RCSB], [https://www.ebi.ac.uk/pdbsum/1kew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kew ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTDP-glucose_4,6-dehydratase dTDP-glucose 4,6-dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.46 4.2.1.46] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1kew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kew OCA], [http://pdbe.org/1kew PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kew RCSB], [http://www.ebi.ac.uk/pdbsum/1kew PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kew ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RMLB_SALTY RMLB_SALTY]] Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction.<ref>PMID:11796113</ref>
[https://www.uniprot.org/uniprot/RMLB_SALTY RMLB_SALTY] Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction.<ref>PMID:11796113</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus typhimurium loeffler 1892]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: DTDP-glucose 4,6-dehydratase]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Allard, S T.M]]
[[Category: Allard STM]]
[[Category: Allen, A G]]
[[Category: Allen AG]]
[[Category: Beis, K]]
[[Category: Beis K]]
[[Category: Giraud, M F]]
[[Category: Giraud M-F]]
[[Category: Graninger, M]]
[[Category: Graninger M]]
[[Category: Gross, J W]]
[[Category: Gross JW]]
[[Category: Hegeman, A D]]
[[Category: Hegeman AD]]
[[Category: Messner, P]]
[[Category: Messner P]]
[[Category: Naismith, J H]]
[[Category: Naismith JH]]
[[Category: Whitfield, C]]
[[Category: Whitfield C]]
[[Category: Lyase]]
[[Category: Rossmann fold]]

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