1k39: Difference between revisions

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[[Image:1k39.jpg|left|200px]]


{{Structure
==The structure of yeast delta3-delta2-enoyl-COA isomerase complexed with octanoyl-COA==
|PDB= 1k39 |SIZE=350|CAPTION= <scene name='initialview01'>1k39</scene>, resolution 3.29&Aring;
<StructureSection load='1k39' size='340' side='right'caption='[[1k39]], [[Resolution|resolution]] 3.29&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=CO8:OCTANOYL-COENZYME A'>CO8</scene>
<table><tr><td colspan='2'>[[1k39]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K39 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dodecenoyl-CoA_isomerase Dodecenoyl-CoA isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.3.8 5.3.3.8]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.29&#8491;</td></tr>
|GENE= ECI1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO8:OCTANOYL-COENZYME+A'>CO8</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k39 OCA], [https://pdbe.org/1k39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k39 RCSB], [https://www.ebi.ac.uk/pdbsum/1k39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k39 ProSAT]</span></td></tr>
 
</table>
'''The structure of yeast delta3-delta2-enoyl-COA isomerase complexed with octanoyl-COA'''
== Function ==
 
[https://www.uniprot.org/uniprot/ECI1_YEAST ECI1_YEAST] Essential for the beta oxidation of unsaturated fatty acids.<ref>PMID:9837886</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
1K39 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K39 OCA].  
Check<jmol>
[[Category: Dodecenoyl-CoA isomerase]]
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k3/1k39_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k39 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Geerlof A]]
[[Category: Geerlof, A.]]
[[Category: Hiltunen JK]]
[[Category: Hiltunen, J K.]]
[[Category: Mursula AM]]
[[Category: Mursula, A M.]]
[[Category: Wierenga RK]]
[[Category: Wierenga, R K.]]
[[Category: CO8]]
[[Category: PO4]]
[[Category: beta-beta-alpha spiral]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:11:58 2008''

Latest revision as of 11:49, 16 August 2023

The structure of yeast delta3-delta2-enoyl-COA isomerase complexed with octanoyl-COAThe structure of yeast delta3-delta2-enoyl-COA isomerase complexed with octanoyl-COA

Structural highlights

1k39 is a 3 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.29Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ECI1_YEAST Essential for the beta oxidation of unsaturated fatty acids.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Geisbrecht BV, Zhu D, Schulz K, Nau K, Morrell JC, Geraghty M, Schulz H, Erdmann R, Gould SJ. Molecular characterization of Saccharomyces cerevisiae Delta3, Delta2-enoyl-CoA isomerase. J Biol Chem. 1998 Dec 11;273(50):33184-91. PMID:9837886

1k39, resolution 3.29Å

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