1jo8: Difference between revisions

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==Structural analysis of the yeast actin binding protein Abp1 SH3 domain==
==Structural analysis of the yeast actin binding protein Abp1 SH3 domain==
<StructureSection load='1jo8' size='340' side='right' caption='[[1jo8]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='1jo8' size='340' side='right'caption='[[1jo8]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1jo8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JO8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1jo8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JO8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jo8 OCA], [http://pdbe.org/1jo8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jo8 RCSB], [http://www.ebi.ac.uk/pdbsum/1jo8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jo8 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jo8 OCA], [https://pdbe.org/1jo8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jo8 RCSB], [https://www.ebi.ac.uk/pdbsum/1jo8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jo8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ABP1_YEAST ABP1_YEAST]] Regulates ARP2/3 complex-mediated actin assembly. Recruits ARP2/3 complex to sides of preexisting actin filaments, which may promote nucleation or stabilization of filament branches. Binds to actin filaments, but not actin monomers. Actin binding is required for ARP2/3 complex activation. May also have a role in linking the actin cytoskeleton to endocytosis. recruits components of the endocytotic machinery to cortical actin patches, known sites of endocytosis.<ref>PMID:11331312</ref>
[https://www.uniprot.org/uniprot/ABP1_YEAST ABP1_YEAST] Regulates ARP2/3 complex-mediated actin assembly. Recruits ARP2/3 complex to sides of preexisting actin filaments, which may promote nucleation or stabilization of filament branches. Binds to actin filaments, but not actin monomers. Actin binding is required for ARP2/3 complex activation. May also have a role in linking the actin cytoskeleton to endocytosis. recruits components of the endocytotic machinery to cortical actin patches, known sites of endocytosis.<ref>PMID:11331312</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Castagnoli, L]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Cesareni, G]]
[[Category: Castagnoli L]]
[[Category: Cope, M J]]
[[Category: Cesareni G]]
[[Category: Douangamath, A]]
[[Category: Cope MJ]]
[[Category: Drubin, D G]]
[[Category: Douangamath A]]
[[Category: Fazi, B]]
[[Category: Drubin DG]]
[[Category: Ferracuti, S]]
[[Category: Fazi B]]
[[Category: Schirwitz, K]]
[[Category: Ferracuti S]]
[[Category: Wilmanns, M]]
[[Category: Schirwitz K]]
[[Category: Zucconi, A]]
[[Category: Wilmanns M]]
[[Category: Sh3 domain actin-binding-protein]]
[[Category: Zucconi A]]
[[Category: Structural protein]]

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