1j7j: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
New page: left|200px<br /><applet load="1j7j" size="450" color="white" frame="true" align="right" spinBox="true" caption="1j7j, resolution 2.3Å" /> '''Crystal Structure of ...
 
No edit summary
 
(15 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1j7j.jpg|left|200px]]<br /><applet load="1j7j" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1j7j, resolution 2.3&Aring;" />
'''Crystal Structure of the HPRT from Salmonella typhimurium'''<br />


==About this Structure==
==Crystal Structure of the HPRT from Salmonella typhimurium==
1J7J is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with MG as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1J7J OCA].
<StructureSection load='1j7j' size='340' side='right'caption='[[1j7j]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
[[Category: Hypoxanthine phosphoribosyltransferase]]
== Structural highlights ==
[[Category: Salmonella typhimurium]]
<table><tr><td colspan='2'>[[1j7j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J7J FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
[[Category: Eakin, A.E.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[Category: Focia, P.J.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j7j OCA], [https://pdbe.org/1j7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j7j RCSB], [https://www.ebi.ac.uk/pdbsum/1j7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j7j ProSAT]</span></td></tr>
[[Category: Lee, C.C.]]
</table>
[[Category: Spraggon, G.]]
== Function ==
[[Category: MG]]
[https://www.uniprot.org/uniprot/HPRT_SALTY HPRT_SALTY] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine (By similarity).
[[Category: glycosyltransferase]]
== Evolutionary Conservation ==
[[Category: nucleotide metabolism]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: phosphoribosyltransferase]]
Check<jmol>
[[Category: purine salvage]]
  <jmolCheckbox>
[[Category: transferase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j7/1j7j_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j7j ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 17:59:29 2007''
==See Also==
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Eakin AE]]
[[Category: Focia PJ]]
[[Category: Lee CC]]
[[Category: Spraggon G]]

Latest revision as of 11:36, 16 August 2023

Crystal Structure of the HPRT from Salmonella typhimuriumCrystal Structure of the HPRT from Salmonella typhimurium

Structural highlights

1j7j is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HPRT_SALTY Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1j7j, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1j7j&oldid=3827953"