5hjd: Difference between revisions

<StructureSection load='5hjd' size='340' side='right'caption='[[5hjd]], [[Resolution|resolution]] 2.81&Aring;' scene=''>

<table><tr><td colspan='2'>[[5hjd]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HJD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HJD FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.806&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=KCR:N-6-CROTONYL-L-LYSINE'>KCR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hjd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hjd OCA], [https://pdbe.org/5hjd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hjd RCSB], [https://www.ebi.ac.uk/pdbsum/5hjd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hjd ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/AF9_HUMAN AF9_HUMAN] A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9;11)(p22;q23) with KMT2A/MLL1. The result is a rogue activator protein.

[https://www.uniprot.org/uniprot/AF9_HUMAN AF9_HUMAN] Component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.<ref>PMID:20159561</ref> <ref>PMID:20471948</ref>  

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Guan HP]]

[[Category: Li HT]]

[[Category: Li YY]]

[[Category: Zhao D]]