5hde: Difference between revisions

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New page: '''Unreleased structure''' The entry 5hde is ON HOLD Authors: Dong, Hui, Li, Sheng, Shi, Junchao Description: Crystal Structure of PTPN12 Catalytic Domain [[Category: Unreleased Struct...
 
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'''Unreleased structure'''


The entry 5hde is ON HOLD
==Crystal Structure of PTPN12 Catalytic Domain==
<StructureSection load='5hde' size='340' side='right'caption='[[5hde]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5hde]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HDE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.62&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSP:S-PHOSPHOCYSTEINE'>CSP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hde OCA], [https://pdbe.org/5hde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hde RCSB], [https://www.ebi.ac.uk/pdbsum/5hde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hde ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTN12_HUMAN PTN12_HUMAN] Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.<ref>PMID:17329398</ref>


Authors: Dong, Hui, Li, Sheng, Shi, Junchao
==See Also==
 
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
Description: Crystal Structure of PTPN12 Catalytic Domain
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Dong, Hui, Li, Sheng, Shi, Junchao]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Dong H]]
[[Category: Li S]]
[[Category: Shi J]]

Latest revision as of 10:32, 9 August 2023

Crystal Structure of PTPN12 Catalytic DomainCrystal Structure of PTPN12 Catalytic Domain

Structural highlights

5hde is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.62Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PTN12_HUMAN Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.[1]

See Also

References

  1. ↑ Sahu SN, Nunez S, Bai G, Gupta A. Interaction of Pyk2 and PTP-PEST with leupaxin in prostate cancer cells. Am J Physiol Cell Physiol. 2007 Jun;292(6):C2288-96. Epub 2007 Feb 28. PMID:17329398 doi:http://dx.doi.org/10.1152/ajpcell.00503.2006

5hde, resolution 1.62Å

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