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[[Image:1vew.jpg|left|200px]]


{{Structure
==MANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI==
|PDB= 1vew |SIZE=350|CAPTION= <scene name='initialview01'>1vew</scene>, resolution 2.1&Aring;
<StructureSection load='1vew' size='340' side='right'caption='[[1vew]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
|SITE= <scene name='pdbsite=MN1:Mn-Bound+Active+Site+On+Chain+A.+Catalytic+Redox+Center'>MN1</scene>, <scene name='pdbsite=MN2:Mn-Bound+Active+Site+On+Chain+B.+Catalytic+Redox+Center'>MN2</scene>, <scene name='pdbsite=MN3:Mn-Bound+Active+Site+On+Chain+C.+Catalytic+Redox+Center'>MN3</scene> and <scene name='pdbsite=MN4:Mn-Bound+Active+Site+On+Chain+D.+Catalytic+Redox+Center'>MN4</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=OH:HYDROXIDE ION'>OH</scene>
<table><tr><td colspan='2'>[[1vew]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VEW FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OH:HYDROXIDE+ION'>OH</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vew OCA], [https://pdbe.org/1vew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vew RCSB], [https://www.ebi.ac.uk/pdbsum/1vew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vew ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/1vew_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vew ConSurf].
<div style="clear:both"></div>


'''MANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI'''
==See Also==
 
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1VEW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VEW OCA].
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Superoxide dismutase]]
[[Category: Baker EN]]
[[Category: Baker, E N.]]
[[Category: Baker HM]]
[[Category: Baker, H M.]]
[[Category: Edwards RA]]
[[Category: Edwards, R A.]]
[[Category: Jameson GB]]
[[Category: Jameson, G B.]]
[[Category: Whittaker JW]]
[[Category: Whittaker, J W.]]
[[Category: Whittaker MM]]
[[Category: Whittaker, M M.]]
[[Category: MN]]
[[Category: OH]]
[[Category: dna binding]]
[[Category: manganese enzyme]]
[[Category: metalloprotein]]
[[Category: oxidoreductase]]
[[Category: superoxide dismutase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:44:40 2008''

Latest revision as of 09:37, 9 August 2023

MANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLIMANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI

Structural highlights

1vew is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SODM_ECOLI Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1vew, resolution 2.10Å

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