1idt: Difference between revisions

<table><tr><td colspan='2'>[[1idt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IDT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IDT FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CB1:5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE'>CB1</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1idt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1idt OCA], [https://pdbe.org/1idt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1idt RCSB], [https://www.ebi.ac.uk/pdbsum/1idt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1idt ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/NFSB_ECOLI NFSB_ECOLI] Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.<ref>PMID:15684426</ref>  

*[[Nitroreductase 3D structures|Nitroreductase 3D structures]]

[[Category: Escherichia coli]]

[[Category: Denny WA]]

[[Category: Johansson E]]

[[Category: Neidle S]]

[[Category: Parkinson GN]]