1hw5: Difference between revisions

<table><tr><td colspan='2'>[[1hw5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HW5 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hw5 OCA], [https://pdbe.org/1hw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hw5 RCSB], [https://www.ebi.ac.uk/pdbsum/1hw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hw5 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref>  

[[Category: Escherichia coli]]

[[Category: Chu SY]]

[[Category: Gilliland GL]]

[[Category: Gorshkova I]]

[[Category: Shi Y]]

[[Category: Tordova M]]