1hqz: Difference between revisions

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<StructureSection load='1hqz' size='340' side='right'caption='[[1hqz]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1hqz' size='340' side='right'caption='[[1hqz]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1hqz]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HQZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1hqz]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HQZ FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hqz OCA], [http://pdbe.org/1hqz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hqz RCSB], [http://www.ebi.ac.uk/pdbsum/1hqz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hqz ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/1hqz TOPSAN]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hqz OCA], [https://pdbe.org/1hqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hqz RCSB], [https://www.ebi.ac.uk/pdbsum/1hqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hqz ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1hqz TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ABP1_YEAST ABP1_YEAST]] Regulates ARP2/3 complex-mediated actin assembly. Recruits ARP2/3 complex to sides of preexisting actin filaments, which may promote nucleation or stabilization of filament branches. Binds to actin filaments, but not actin monomers. Actin binding is required for ARP2/3 complex activation. May also have a role in linking the actin cytoskeleton to endocytosis. recruits components of the endocytotic machinery to cortical actin patches, known sites of endocytosis.<ref>PMID:11331312</ref>
[https://www.uniprot.org/uniprot/ABP1_YEAST ABP1_YEAST] Regulates ARP2/3 complex-mediated actin assembly. Recruits ARP2/3 complex to sides of preexisting actin filaments, which may promote nucleation or stabilization of filament branches. Binds to actin filaments, but not actin monomers. Actin binding is required for ARP2/3 complex activation. May also have a role in linking the actin cytoskeleton to endocytosis. recruits components of the endocytotic machinery to cortical actin patches, known sites of endocytosis.<ref>PMID:11331312</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Burley, S K]]
[[Category: Almo SC]]
[[Category: Drubin, D G]]
[[Category: Burley SK]]
[[Category: Fedorov, A A]]
[[Category: Drubin DG]]
[[Category: Mahoney, N]]
[[Category: Fedorov AA]]
[[Category: Structural genomic]]
[[Category: Mahoney N]]
[[Category: Strokopytov, B V]]
[[Category: Strokopytov BV]]
[[Category: Actin binding]]
[[Category: Cofilin homology domain]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Structural protein]]

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