1g5u: Difference between revisions

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-[[Image:1g5u.gif|left|200px]]
-<!--
+==LATEX PROFILIN HEVB8==
-The line below this paragraph, containing "STRUCTURE_1g5u", creates the "Structure Box" on the page.
+<StructureSection load='1g5u' size='340' side='right'caption='[[1g5u]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1g5u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hevea_brasiliensis Hevea brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G5U FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-{{STRUCTURE_1g5u|  PDB=1g5u  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g5u OCA], [https://pdbe.org/1g5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g5u RCSB], [https://www.ebi.ac.uk/pdbsum/1g5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g5u ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PROF6_HEVBR PROF6_HEVBR] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g5/1g5u_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g5u ConSurf].
+<div style="clear:both"></div>
-'''LATEX PROFILIN HEVB8'''
+==See Also==
+*[[Profilin 3D Structures|Profilin 3D Structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-G5U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hevea_brasiliensis Hevea brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G5U OCA].
 [[Category: Hevea brasiliensis]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Almo, S C.]]
+[[Category: Almo SC]]
-[[Category: Breiteneder, H.]]
+[[Category: Breiteneder H]]
-[[Category: Fedorov, A A.]]
+[[Category: Fedorov AA]]
-[[Category: Fedorov, E V.]]
+[[Category: Fedorov EV]]
-[[Category: Ganglberger, E.]]
+[[Category: Ganglberger E]]
-[[Category: Actin-binding protein]]
-[[Category: Allergen]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 17:10:24 2008''