1fhj: Difference between revisions

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-{{Seed}}
-[[Image:1fhj.png|left|200px]]
-<!--
+==CRYSTAL STRUCTURE OF AQUOMET HEMOGLOBIN-I OF THE MANED WOLF (CHRYSOCYON BRACHYURUS) AT 2.0 RESOLUTION.==
-The line below this paragraph, containing "STRUCTURE_1fhj", creates the "Structure Box" on the page.
+<StructureSection load='1fhj' size='340' side='right'caption='[[1fhj]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1fhj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chrysocyon_brachyurus Chrysocyon brachyurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FHJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FHJ FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-{{STRUCTURE_1fhj|  PDB=1fhj  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fhj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fhj OCA], [https://pdbe.org/1fhj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fhj RCSB], [https://www.ebi.ac.uk/pdbsum/1fhj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fhj ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HBA_CHRBR HBA_CHRBR] Involved in oxygen transport from the lung to the various peripheral tissues.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fh/1fhj_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fhj ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Crystal structure of hemoglobin isolated from the Brazilian maned wolf (Chrysocyon brachyurus) was determined using standard molecular replacement technique and refined using maximum-likelihood and simulated annealing protocols to 1.87A resolution. Structural and functional comparisons between hemoglobins from the Chrysocyon brachyurus and Homo sapiens are discussed, in order to provide further insights in the comparative biochemistry of vertebrate hemoglobins.
-===CRYSTAL STRUCTURE OF AQUOMET HEMOGLOBIN-I OF THE MANED WOLF (CHRYSOCYON BRACHYURUS) AT 2.0 RESOLUTION.===
+Crystal structure of hemoglobin from the maned wolf (Chrysocyon brachyurus) using synchrotron radiation.,Fadel V, Canduri F, Olivieri JR, Smarra AL, Colombo MF, Bonilla-Rodriguez GO, de Azevedo WF Jr Protein Pept Lett. 2003 Dec;10(6):551-9. PMID:14683506<ref>PMID:14683506</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 1fhj" style="background-color:#fffaf0;"></div>
-<!--
+==See Also==
-The line below this paragraph, {{ABSTRACT_PUBMED_14683506}}, adds the Publication Abstract to the page
+*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 14683506 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_14683506}}
+__TOC__
+</StructureSection>
-==About this Structure==
-FHJ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Chrysocyon_brachyurus Chrysocyon brachyurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FHJ OCA].
-==Reference==
-Crystal structure of hemoglobin from the maned wolf (Chrysocyon brachyurus) using synchrotron radiation., Fadel V, Canduri F, Olivieri JR, Smarra AL, Colombo MF, Bonilla-Rodriguez GO, de Azevedo WF Jr, Protein Pept Lett. 2003 Dec;10(6):551-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14683506 14683506]
 [[Category: Chrysocyon brachyurus]]
-[[Category: Protein complex]]
+[[Category: Large Structures]]
-[[Category: Azevedo, W F.de.]]
+[[Category: Fadel V]]
-[[Category: Fadel, V.]]
+[[Category: De Azevedo WF]]
-[[Category: Hemoglobin]]
-[[Category: Maned wolf]]
-[[Category: Metahemoglobin]]
-[[Category: X-ray diffraction]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 03:15:24 2008''