1f2k: Difference between revisions

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-{{Seed}}
-[[Image:1f2k.png|left|200px]]
-<!--
+==CRYSTAL STRUCTURE OF ACANTHAMOEBA CASTELLANII PROFILIN II, CUBIC CRYSTAL FORM==
-The line below this paragraph, containing "STRUCTURE_1f2k", creates the "Structure Box" on the page.
+<StructureSection load='1f2k' size='340' side='right'caption='[[1f2k]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1f2k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_castellanii Acanthamoeba castellanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F2K FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f2k OCA], [https://pdbe.org/1f2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f2k RCSB], [https://www.ebi.ac.uk/pdbsum/1f2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f2k ProSAT]</span></td></tr>
-{{STRUCTURE_1f2k|  PDB=1f2k  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PROF2_ACACA PROF2_ACACA] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/1f2k_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f2k ConSurf].
+<div style="clear:both"></div>
-===CRYSTAL STRUCTURE OF ACANTHAMOEBA CASTELLANII PROFILIN II, CUBIC CRYSTAL FORM===
+==See Also==
+*[[Profilin 3D Structures|Profilin 3D Structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-F2K is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Acanthamoeba_castellanii Acanthamoeba castellanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F2K OCA].
 [[Category: Acanthamoeba castellanii]]
-[[Category: Almo, S C.]]
+[[Category: Large Structures]]
-[[Category: Fedorov, A A.]]
+[[Category: Almo SC]]
-[[Category: Kaiser, D A.]]
+[[Category: Fedorov AA]]
-[[Category: Mahoney, N.]]
+[[Category: Kaiser DA]]
-[[Category: Shi, W.]]
+[[Category: Mahoney N]]
-[[Category: Actin-binding protein]]
+[[Category: Shi W]]
-[[Category: Pip2 binding protein]]
-[[Category: Poly-l-proline binding protein]]
-[[Category: Seven-stranded incomplete antiparallel up-and-down beta barrel]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:20:30 2009''