1ce7: Difference between revisions

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OCA

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 ==MISTLETOE LECTIN I FROM VISCUM ALBUM==
-<StructureSection load='1ce7' size='340' side='right' caption='[[1ce7]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
+<StructureSection load='1ce7' size='340' side='right'caption='[[1ce7]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1ce7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Viscum_album Viscum album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CE7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CE7 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1ce7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Viscum_album Viscum album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CE7 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ce7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ce7 OCA], [http://pdbe.org/1ce7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ce7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ce7 PDBsum]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ce7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ce7 OCA], [https://pdbe.org/1ce7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ce7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ce7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ce7 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/ML1_VISAL ML1_VISAL]] The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. The B chain binds to cell receptors and probably facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (lectin activity). Inhibits growth of the human tumor cell line Molt4.<ref>PMID:15182350</ref> <ref>PMID:15001393</ref> <ref>PMID:1450445</ref>
+[https://www.uniprot.org/uniprot/ML4_VISAL ML4_VISAL] The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. The B chain binds to cell receptors and probably facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (lectin activity). Inhibits growth of the human tumor cell line Molt4.<ref>PMID:15001393</ref> <ref>PMID:1450445</ref> [UniProtKB:P81446]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/1ce7_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/1ce7_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ce7 ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 31: / Line 33: @@
 __TOC__
 </StructureSection>
+[[Category: Large Structures]]
 [[Category: Viscum album]]
-[[Category: Betzel, C]]
+[[Category: Betzel C]]
-[[Category: Eschenburg, S]]
+[[Category: Eschenburg S]]
-[[Category: Konareva, N]]
+[[Category: Konareva N]]
-[[Category: Kornilov, V]]
+[[Category: Kornilov V]]
-[[Category: Krauspenhaar, R]]
+[[Category: Krauspenhaar R]]
-[[Category: Maier, T]]
+[[Category: Maier T]]
-[[Category: Mikailova, I]]
+[[Category: Mikailova I]]
-[[Category: Mikhailov, A]]
+[[Category: Mikhailov A]]
-[[Category: Perbandt, M]]
+[[Category: Perbandt M]]
-[[Category: Singh, T P]]
+[[Category: Singh TP]]
-[[Category: Stoeva, S]]
+[[Category: Stoeva S]]
-[[Category: Voelter, W]]
+[[Category: Voelter W]]
-[[Category: Wacker, R]]
+[[Category: Wacker R]]
-[[Category: Ribosome]]
-[[Category: Ribosome-inactivating protein type ii]]