1bsk: Difference between revisions

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<StructureSection load='1bsk' size='340' side='right'caption='[[1bsk]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='1bsk' size='340' side='right'caption='[[1bsk]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1bsk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BSK FirstGlance]. <br>
<table><tr><td colspan='2'>[[1bsk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BSK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLN:(S)-2-(PHOSPHONOXY)CAPROYL-L-LEUCYL-P-NITROANILIDE'>MLN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-formylmethionylaminoacyl-tRNA_deformylase N-formylmethionylaminoacyl-tRNA deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.27 3.5.1.27] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLN:(S)-2-(PHOSPHONOXY)CAPROYL-L-LEUCYL-P-NITROANILIDE'>MLN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bsk OCA], [http://pdbe.org/1bsk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bsk RCSB], [http://www.ebi.ac.uk/pdbsum/1bsk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bsk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bsk OCA], [https://pdbe.org/1bsk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bsk RCSB], [https://www.ebi.ac.uk/pdbsum/1bsk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bsk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]  
[https://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: N-formylmethionylaminoacyl-tRNA deformylase]]
[[Category: Chan MK]]
[[Category: Chan, M K]]
[[Category: Gong W]]
[[Category: Gong, W]]
[[Category: Hao B]]
[[Category: Hao, B]]
[[Category: Hu Y]]
[[Category: Hu, Y]]
[[Category: Pei D]]
[[Category: Pei, D]]
[[Category: Rajagopalan PT]]
[[Category: Rajagopalan, P T]]
[[Category: Deformylase]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]
[[Category: Metalloproteinase]]

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