8jpd: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 8jpd is ON HOLD
+==Focused refinement structure of GRK2 in NTSR1-GRK2-Galpha(q) complexes==
+<StructureSection load='8jpd' size='340' side='right'caption='[[8jpd]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
-Authors: Duan, J., Liu, H., Zhao, F., Yuan, Q., Ji, Y., Xu, H.E.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8jpd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JPD FirstGlance]. <br>
-Description: Focused refinement structure of GRK2 in NTSR1-GRK2-Galpha(q) complexes
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=STU:STAUROSPORINE'>STU</scene></td></tr>
-[[Category: Xu, H.E]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jpd OCA], [https://pdbe.org/8jpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jpd RCSB], [https://www.ebi.ac.uk/pdbsum/8jpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jpd ProSAT]</span></td></tr>
-[[Category: Duan, J]]
+</table>
-[[Category: Zhao, F]]
+== Function ==
-[[Category: Liu, H]]
+[https://www.uniprot.org/uniprot/ARBK1_BOVIN ARBK1_BOVIN] Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (By similarity).
-[[Category: Yuan, Q]]
+__TOC__
-[[Category: Ji, Y]]
+</StructureSection>
+[[Category: Bos taurus]]
+[[Category: Large Structures]]
+[[Category: Duan J]]
+[[Category: Ji Y]]
+[[Category: Liu H]]
+[[Category: Xu HE]]
+[[Category: Yuan Q]]
+[[Category: Zhao F]]