8bkb: Difference between revisions

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'''Unreleased structure'''


The entry 8bkb is ON HOLD
==Cryo-EM structure of mouse heavy-chain apoferritin at 2.2 A plunged 205ms after mixing with b-galactosidase==
 
<StructureSection load='8bkb' size='340' side='right'caption='[[8bkb]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
Authors: Torino, S., Dhurandhar, M., Efremov, R.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8bkb]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BKB FirstGlance]. <br>
Description: Cryo-EM structure of mouse heavy-chain apoferritin at 2.2 A plunged 205ms after mixing with b-galactosidase
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
[[Category: Efremov, R]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bkb OCA], [https://pdbe.org/8bkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bkb RCSB], [https://www.ebi.ac.uk/pdbsum/8bkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bkb ProSAT]</span></td></tr>
[[Category: Dhurandhar, M]]
</table>
[[Category: Torino, S]]
== Function ==
[https://www.uniprot.org/uniprot/FRIH_MOUSE FRIH_MOUSE] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.<ref>PMID:19154717</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Dhurandhar M]]
[[Category: Efremov R]]
[[Category: Torino S]]

Latest revision as of 08:24, 9 August 2023

Cryo-EM structure of mouse heavy-chain apoferritin at 2.2 A plunged 205ms after mixing with b-galactosidaseCryo-EM structure of mouse heavy-chain apoferritin at 2.2 A plunged 205ms after mixing with b-galactosidase

Structural highlights

8bkb is a 24 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FRIH_MOUSE Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.[1]

References

  1. ↑ Li JY, Paragas N, Ned RM, Qiu A, Viltard M, Leete T, Drexler IR, Chen X, Sanna-Cherchi S, Mohammed F, Williams D, Lin CS, Schmidt-Ott KM, Andrews NC, Barasch J. Scara5 is a ferritin receptor mediating non-transferrin iron delivery. Dev Cell. 2009 Jan;16(1):35-46. doi: 10.1016/j.devcel.2008.12.002. PMID:19154717 doi:http://dx.doi.org/10.1016/j.devcel.2008.12.002

8bkb, resolution 2.20Å

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