7xgi: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 7xgi is ON HOLD
+==COMT SAH Mg opicapone complex==
+<StructureSection load='7xgi' size='340' side='right'caption='[[7xgi]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors: Takebe, K., Kuwada-Kusunose, T., Suzuki, M., Uzawa, N., Iijima, H.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7xgi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XGI FirstGlance]. <br>
-Description: COMT SAH Mg opicapone complex
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DNI:5-[3-[2,5-bis(chloranyl)-4,6-dimethyl-1-oxidanidyl-pyridin-1-ium-3-yl]-1,2,4-oxadiazol-5-yl]-3-nitro-benzene-1,2-diol'>DNI</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-[[Category: Uzawa, N]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xgi OCA], [https://pdbe.org/7xgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xgi RCSB], [https://www.ebi.ac.uk/pdbsum/7xgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xgi ProSAT]</span></td></tr>
-[[Category: Suzuki, M]]
+</table>
-[[Category: Kuwada-Kusunose, T]]
+== Function ==
-[[Category: Takebe, K]]
+[https://www.uniprot.org/uniprot/COMT_RAT COMT_RAT] Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
-[[Category: Iijima, H]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Rattus norvegicus]]
+[[Category: Iijima H]]
+[[Category: Kuwada-Kusunose T]]
+[[Category: Suzuki M]]
+[[Category: Takebe K]]
+[[Category: Uzawa N]]