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==ENGRAILED HOMEODOMAIN DNA COMPLEX== | ==ENGRAILED HOMEODOMAIN DNA COMPLEX== | ||
<StructureSection load='3hdd' size='340' side='right' caption='[[3hdd]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='3hdd' size='340' side='right'caption='[[3hdd]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3hdd]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3hdd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HDD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HDD FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hdd OCA], [https://pdbe.org/3hdd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hdd RCSB], [https://www.ebi.ac.uk/pdbsum/3hdd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hdd ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Drosophila melanogaster]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Chambers KA]] | ||
[[Category: | [[Category: Fraenkel E]] | ||
[[Category: | [[Category: Pabo CO]] | ||
[[Category: | [[Category: Rould MA]] | ||