1bkp: Difference between revisions

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 <StructureSection load='1bkp' size='340' side='right'caption='[[1bkp]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1bkp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BKP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1BKP FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1bkp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BKP FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">THYA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bkp OCA], [https://pdbe.org/1bkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bkp RCSB], [https://www.ebi.ac.uk/pdbsum/1bkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bkp ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1bkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bkp OCA], [http://pdbe.org/1bkp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bkp RCSB], [http://www.ebi.ac.uk/pdbsum/1bkp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bkp ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/TYSY1_BACSU TYSY1_BACSU] Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.[HAMAP-Rule:MF_00008]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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 __TOC__
 </StructureSection>
-[[Category: Vibrio subtilis ehrenberg 1835]]
+[[Category: Bacillus subtilis]]
 [[Category: Large Structures]]
-[[Category: Thymidylate synthase]]
+[[Category: Santi DV]]
-[[Category: Santi, D V]]
+[[Category: Schellenberger U]]
-[[Category: Schellenberger, U]]
+[[Category: Stout TJ]]
-[[Category: Stout, T J]]
+[[Category: Stroud RM]]
-[[Category: Stroud, R M]]
-[[Category: Dtmp synthase]]
-[[Category: Methyltransferase]]