1akh: Difference between revisions

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<StructureSection load='1akh' size='340' side='right'caption='[[1akh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='1akh' size='340' side='right'caption='[[1akh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1akh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AKH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1AKH FirstGlance]. <br>
<table><tr><td colspan='2'>[[1akh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AKH FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAT A1 RESIDUES 66 - 126 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824]), MAT ALPHA2 RESIDUES 128 - 210 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1akh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1akh OCA], [http://pdbe.org/1akh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1akh RCSB], [http://www.ebi.ac.uk/pdbsum/1akh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1akh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1akh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1akh OCA], [https://pdbe.org/1akh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1akh RCSB], [https://www.ebi.ac.uk/pdbsum/1akh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1akh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MTAL2_YEAST MTAL2_YEAST]] Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Transcriptional corepressor that binds cooperatively with MCM1 to a 31-basepair DNA sequence termed the a-specific gene (asg) operator, to repress the transcription of a-cell-specific genes. Additionally, in a/alpha diploid cells, binds cooperatively with the A1 protein to a 21-basepair DNA sequence termed the haploid-specific gene (hsg) operator, to repress transcription of haploid-specific genes and of MATALPHA1.<ref>PMID:8664541</ref>
[https://www.uniprot.org/uniprot/MATA1_YEASX MATA1_YEASX] Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Transcriptional corepressor that, in a/alpha diploid cells, binds cooperatively with the ALPHA2 protein to a 21-bp DNA sequence termed the haploid-specific gene (hsg) operator, to repress transcription of haploid-specific genes and of MATALPHA1.<ref>PMID:8664541</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Jin, Y]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Li, T]]
[[Category: Jin Y]]
[[Category: Vershon, A K]]
[[Category: Li T]]
[[Category: Wolberger, C]]
[[Category: Vershon AK]]
[[Category: Complex]]
[[Category: Wolberger C]]
[[Category: Dna]]
[[Category: Dna binding protein-dna complex]]
[[Category: Dna-binding protein]]
[[Category: Transcription regulation]]

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