5g2v: Difference between revisions

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<StructureSection load='5g2v' size='340' side='right'caption='[[5g2v]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
<StructureSection load='5g2v' size='340' side='right'caption='[[5g2v]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5g2v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bactn Bactn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2V OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5G2V FirstGlance]. <br>
<table><tr><td colspan='2'>[[5g2v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5G2V FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.39&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5g2t|5g2t]], [[5g2u|5g2u]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylglucosamine-6-sulfatase N-acetylglucosamine-6-sulfatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.6.14 3.1.6.14] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5g2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2v OCA], [https://pdbe.org/5g2v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5g2v RCSB], [https://www.ebi.ac.uk/pdbsum/5g2v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2v ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5g2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2v OCA], [http://pdbe.org/5g2v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g2v RCSB], [http://www.ebi.ac.uk/pdbsum/5g2v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLCSF_BACTN GLCSF_BACTN] Exosulfatase involved in the degradation of the glycosaminoglycan (GAG) heparan sulfate (HS). Catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units (PubMed:25002587). GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B.thetaiotaomicron in the host gastrointestinal tract (PubMed:25002587).<ref>PMID:25002587</ref> <ref>PMID:25002587</ref>
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bactn]]
[[Category: Bacteroides thetaiotaomicron VPI-5482]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: N-acetylglucosamine-6-sulfatase]]
[[Category: Basle A]]
[[Category: Basle, A]]
[[Category: Bolam DN]]
[[Category: Bolam, D N]]
[[Category: Cartmell A]]
[[Category: Cartmell, A]]
[[Category: Crouch LI]]
[[Category: Crouch, L I]]
[[Category: Czjzek M]]
[[Category: Czjzek, M]]
[[Category: Firbank SJ]]
[[Category: Firbank, S J]]
[[Category: Henrissat B]]
[[Category: Henrissat, B]]
[[Category: Lowe EC]]
[[Category: Lowe, E C]]
[[Category: Murray H]]
[[Category: Murray, H]]
[[Category: Terrapon N]]
[[Category: Terrapon, N]]
[[Category: Thomas S]]
[[Category: Thomas, S]]
[[Category: Turnbull J]]
[[Category: Turnbull, J]]
[[Category: Glycosaminoglycan sulfatase]]
[[Category: Hydrolase]]

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