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==Crystal structure of the Mo-insertase domain Cnx1E from Arabidopsis thaliana in complex with molybdate==
==Crystal structure of the Mo-insertase domain Cnx1E from Arabidopsis thaliana in complex with molybdate==
<StructureSection load='5g2s' size='340' side='right' caption='[[5g2s]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
<StructureSection load='5g2s' size='340' side='right'caption='[[5g2s]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5g2s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G2S FirstGlance]. <br>
<table><tr><td colspan='2'>[[5g2s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5G2S FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MOO:MOLYBDATE+ION'>MOO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.838&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5g2r|5g2r]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MOO:MOLYBDATE+ION'>MOO</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Molybdopterin_molybdotransferase Molybdopterin molybdotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.10.1.1 2.10.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5g2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2s OCA], [https://pdbe.org/5g2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5g2s RCSB], [https://www.ebi.ac.uk/pdbsum/5g2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2s OCA], [http://pdbe.org/5g2s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g2s RCSB], [http://www.ebi.ac.uk/pdbsum/5g2s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CNX1_ARATH CNX1_ARATH]] Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.<ref>PMID:15504727</ref> <ref>PMID:16636046</ref> <ref>PMID:12590921</ref> <ref>PMID:15306815</ref>
[https://www.uniprot.org/uniprot/CNX1_ARATH CNX1_ARATH] Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.<ref>PMID:15504727</ref> <ref>PMID:16636046</ref> <ref>PMID:12590921</ref> <ref>PMID:15306815</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Molybdopterin molybdotransferase]]
[[Category: Arabidopsis thaliana]]
[[Category: Heinz, D W]]
[[Category: Large Structures]]
[[Category: Krausze, J]]
[[Category: Heinz DW]]
[[Category: Kruse, T]]
[[Category: Krausze J]]
[[Category: Mendel, R R]]
[[Category: Kruse T]]
[[Category: Probst, C]]
[[Category: Mendel RR]]
[[Category: Cnx1]]
[[Category: Probst C]]
[[Category: Cnx1e]]
[[Category: Gephe]]
[[Category: Gephyrin]]
[[Category: Mo-insertase]]
[[Category: Moco]]
[[Category: Moea]]
[[Category: Molybdenum cofactor]]
[[Category: Molybdenum metabolism]]
[[Category: Transferase]]

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