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==Crystal structure of JmjC domain of human histone demethylase UTY in complex with succinate==
==Crystal structure of JmjC domain of human histone demethylase UTY in complex with succinate==
<StructureSection load='5fy7' size='340' side='right' caption='[[5fy7]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
<StructureSection load='5fy7' size='340' side='right'caption='[[5fy7]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fy7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FY7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fy7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FY7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fxv|5fxv]], [[5fxw|5fxw]], [[5fxx|5fxx]], [[5fxz|5fxz]], [[5fy0|5fy0]], [[5fy1|5fy1]], [[5fy4|5fy4]], [[5fy5|5fy5]], [[5fy8|5fy8]], [[5fy9|5fy9]], [[5fyb|5fyb]], [[5fyc|5fyc]], [[5fyh|5fyh]], [[5fyi|5fyi]], [[5fym|5fym]], [[5fys|5fys]], [[5fyt|5fyt]], [[5fyu|5fyu]], [[5fyv|5fyv]], [[5fyy|5fyy]], [[5fyz|5fyz]], [[5fz0|5fz0]], [[5fz1|5fz1]], [[5fz3|5fz3]], [[5fz4|5fz4]], [[5fz6|5fz6]], [[5fz7|5fz7]], [[5fz8|5fz8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fy7 OCA], [http://pdbe.org/5fy7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fy7 RCSB], [http://www.ebi.ac.uk/pdbsum/5fy7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fy7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fy7 OCA], [https://pdbe.org/5fy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fy7 RCSB], [https://www.ebi.ac.uk/pdbsum/5fy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fy7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN]] Histone demethylase (By similarity).  
[https://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN] Histone demethylase (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H]]
[[Category: Large Structures]]
[[Category: Bountra, C]]
[[Category: Arrowsmith CH]]
[[Category: Delft, F von]]
[[Category: Bountra C]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Gileadi, C]]
[[Category: Gileadi C]]
[[Category: Johansson, C]]
[[Category: Johansson C]]
[[Category: Krojer, T]]
[[Category: Krojer T]]
[[Category: Kupinska, K]]
[[Category: Kupinska K]]
[[Category: Nowak, R]]
[[Category: Nowak R]]
[[Category: Oppermann, U]]
[[Category: Oppermann U]]
[[Category: Tca intermediate]]
[[Category: Von Delft F]]
[[Category: Transferase]]

Latest revision as of 16:31, 26 July 2023

Crystal structure of JmjC domain of human histone demethylase UTY in complex with succinateCrystal structure of JmjC domain of human histone demethylase UTY in complex with succinate

Structural highlights

5fy7 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.86Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UTY_HUMAN Histone demethylase (By similarity).

5fy7, resolution 1.86Å

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