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==Crystal structure of JmjC domain of human histone demethylase UTY in complex with fumarate== | ==Crystal structure of JmjC domain of human histone demethylase UTY in complex with fumarate== | ||
<StructureSection load='5fxw' size='340' side='right' caption='[[5fxw]], [[Resolution|resolution]] 2.09Å' scene=''> | <StructureSection load='5fxw' size='340' side='right'caption='[[5fxw]], [[Resolution|resolution]] 2.09Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5fxw]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5fxw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FXW FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUM:FUMARIC+ACID'>FUM</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUM:FUMARIC+ACID'>FUM</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fxw OCA], [https://pdbe.org/5fxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fxw RCSB], [https://www.ebi.ac.uk/pdbsum/5fxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fxw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN] Histone demethylase (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: Edwards | [[Category: Edwards A]] | ||
[[Category: Gileadi | [[Category: Gileadi C]] | ||
[[Category: Johansson | [[Category: Johansson C]] | ||
[[Category: Krojer | [[Category: Krojer T]] | ||
[[Category: Kupinska | [[Category: Kupinska K]] | ||
[[Category: Nowak | [[Category: Nowak R]] | ||
[[Category: Oppermann | [[Category: Oppermann U]] | ||
[[Category: | [[Category: Von Delft F]] | ||
Latest revision as of 16:31, 26 July 2023
Crystal structure of JmjC domain of human histone demethylase UTY in complex with fumarateCrystal structure of JmjC domain of human histone demethylase UTY in complex with fumarate
Structural highlights
FunctionUTY_HUMAN Histone demethylase (By similarity). |
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